strattera online




Use AgonyRelief Search to

Find and buy STRATTERA with Search

using AgonyRelief Search

using MultiFind24 Search

Strattera vs Vyvanse

strattera versus vyvanse


Let us compare these two medications. Both Strattera and Vyvanse are used for treatment of ADHD (attention deficit and hyperactivity disorder) in children aged 6 through 12, teenagers, and also for ADD (attention deficit disorder) in both children and adults. Strattera was the first medication approved for adult ADHD. Though, unlike Strattera, when launched, Vyvanse was not officially approved for adult ADHD, the situation changed in June 2007 when Shire PLC (Vyvanse's manufacturer) announced that a supplemental New Drug Application had been submitted to the FDA for the treatment of ADD/ADHD in adults.

Strattera is classified as a non-stimulant drug, while Vyvanse is a stimulant belonging to amphetamines. Together with a well-known Effexor medication, Strattera is in the group of drugs called SNRIs - serotonin-norepinephrine reuptake inhibitors. The medication increases levels of serotonin and norepinephrine by inhibiting their reabsorption into cells in the brain, thus affecting our mood and mind condition. Vyvanse is closely related to Adderall (Adderall XR), both of them having the same active ingredient - lisdexamfetamine dimesylate. The main difference between Vyvanse and Adderall is that Adderall is a mixture of four amphetamine salts, three of which are classified as d-amphetamines and the fourth one is l-amphetamine, while Vyvanse is a 100% d-amphetamine.

Strattera is not a scheduled controlled substance, since it has a much lower potential for abuse than amphetamines. Vyvanse is a schedule II controlled substance. However, it also features a much lower potential for abuse, as compared to other amphetamines due to the fact that it has produces effects when being snorted or injected. The matter is that Vyvanse is a prodrug, i.e. its contents have to pass through the digestive system and the liver to get converted into an active form. Actually, we may say that Vyvanse becomes a sort of Adderall after it is swallowed and digested.

However, all amphetamines are stimulants. When taken in large quantities, they may make one feel "high". Strattera may not. That is why it can be called a safer medication than Vyvanse. But Strattera works slower than Vyvanse and other stimulants. It usually takes several weeks before the body and brain get accustomed to the medication and the desired effects are achieved. During this period of adaptation, the patient may experience a number of unpleasant feelings, such as tiredness, drowsiness, grogginess, etc. The positive effects of Vyvanse are usually observed at once the treatment is started - on condition that the patient is able to respond to the treatment positively.

Some people say that Strattera features more steady effects, making them feel all right throughout the day, while Vyvanse, like other amphetamines, just boosts their abilities for a short period after being taken.

In this "Strattera vs Vyvanse" issue it is quite impossible to give superiority to any of the medications. Strattera works better for some individuals, Vyvanse is more effective and better tolerated by others. It is all a matter of the patient's system and abilities. So the treatment must be individually fitted. That includes selection of medications, dosages and possible combinations of drugs.


One should not take Strattera together with Vyvanse, Wellbutrin, etc unless it is recommended by his or her physician, though the combination of these two medications seems to have no dangerous risks. There point is that the dosages of the medications have to be altered in case they are combined. If they are not decreased to some extent the combined action of the two medications may worsen possible side effects of them both. Generally speaking, it is better to opt for the one you seem to respond to better.

Anyway, there is some evidence that in some children who are extremely hyperactive and impulsive, a combination of Strattera and a stimulant, such as Vyvanse, works better than either medication alone. Also, some patients report that on Strattera they feel rather tired all the time, and on Vyvanse they have more energy though their ability to concentrate is less, and the increased level of energy leads to excessive agitation. But when they take Strattera and Vyvanse together they do not experience the fatigue caused by Strattera and they have a better focus than on Vyvanse itself. But remember, if Strattera and Vyvanse are taken together, their doses have to be properly adjusted.

See also:

  1. Strattera dosage
  2. Strattera and Wellbutrin


Also, any medication may seem to loose some of its efficacy in the course of time, either because the patient gets too much accustomed to it, or due to age-specific changes in the body and brain. It happens that, as times passes, one has to switch over to a different medication because his or her usual one seems to begin working worse than before.

To summarize, we may conclude that the problem of Strattera vs Vyvanse is to be solved individually by each patient together with his or her physician.